Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
نویسندگان
چکیده
This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibrium, leading to a subpopulation of bipolar patients sensitive to arrhythmia.
منابع مشابه
Unmasking of brugada syndrome by lithium.
BACKGROUND The characteristic ECG pattern of ST-segment elevation in V1 and V2 in the Brugada syndrome is dynamic; it is often intermittently present in affected individuals and can be unmasked by sodium channel blockers, including antiarrhythmic drugs and tricyclic antidepressants. We report here 2 patients who developed the Brugada ECG pattern after administration of lithium, a commonly used ...
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015